All You Need to Know About SR9009

What Is SR9009?

As you’ve probably heard before, the human body functions according to what’s known as the circadian rhythm. This rhythm basically refers to a series of patterns that our physical system goes through in a 24-hour period, which occur in synchronicity with the rise and fall of the sun.

There’s a loop mechanism that’s responsible for sustaining the circadian rhythm, and this mechanism works by turning your genes on and off. So, for example, PER and CRY are turned on when the CLOCK and BMAL1 genes are activated. PER and CRY are also able to turn off the BMAL1 and CLOCK before the 24-hour cycle resets.

SR9009 molucule structure

Source: https://en.wikipedia.org/wiki/SR9009

Now, the synthetic drug known as Stenabolic or SR9009 was produced for the sole purpose of understanding the body’s circadian rhythm. Through research done on mice, SR9009 has been shown to reduce anxiety while improving endurance levels and reducing inflammation, weight gain and cholesterol levels. If the same benefits were to be replicated in humans, they would basically mimic the same health-improving effects that workouts have on us. The thing is that SR9009 hasn’t been clinically tested on humans yet so there’s no telling what its side-effects would be, so it’s very concerning to learn that it’s already available for purchase online as a supplement.

Again, the research done on mice shows that the SR9009 compound increases the activity of REV-ERBs, which are also known as agonists that increase the bioavailability of nutrients in the body.

Basically, REV-ERBs are proteins that turn off BMAL1 to restore balance to the body’s internal clock. However, in order for them to work, the heme group has to turn them on, and heme is a tiny compound that’s pervasive throughout the whole body and mainly contains iron.

Thanks to the optimistic results coming out of animal research on SR9009, humans are now using it for bodybuilding purposes, with some even referring to it as “exercise in a bottle.”

The only downside to this is that there’s no real evidence to indicate what the long-term effects of SR9009 would be on humans, and there’s literally zero knowledge on what the side-effects are.

How does SR9009 work?

Thanks to its ability to affect REV-ERB (NR1D1, NR1D2) in the body, SR9009 exhibits numerous health benefits. Based on research done on mice, REV-ERB influences the activity of circadian rhythms through the suppression of BMAL1 to modify the sleeping patterns and the overall activity.

In addition, REV-ERB has also been shown to influence several other aspects of energy production.

Rev-erba-Rev-erb explanation

Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090048/

This is probably because REV-ERB comes from the liver, muscles and fat tissue:

  • Liver: Of the 900 genes that are controlled by a mouse’s circadian rhythm, about 90% can be affected by REV-ERB. Once it starts working, this compound deactivates glucose-producing genes while leaving insulin sensitivity intact. At the same time, it diminishes the body’s inflammatory response while activating the creation of new fat cells.
  • Muscles: REV-ERB automatically boosts mitochondria activity while simultaneously decreasing old mitochondria damage. This process effectively accelerates fat burning.
  • Fat Cells: REV-ERB can also deactivate fat-storing genes, which in turn diminishes the production of triglycerides.

Animal and cell studies that have been done on SR9009 show that:

  • It proliferates oxygen consumption
  • It reduces the production of new fat cells in the liver
  • Bile acid and cholesterol production is considerably reduced
  • There’s a larger number of mitochondria in the muscles
  • The muscles use a higher rate of glucose and fatty acids
  • There’s less fat stored in the muscles

9 SR-9009 Benefits

  1. Can Help Lose Weight

SR9009 has the ability to affect weight loss without augmenting the diet, according to a 7-day study on mice.

SR9009 has also been shown to reduce the amount of cholesterol, triglycerides, insulin and free fatty acids shown in diet-induced obese mice. Whereas, genetically obese mice stopped gaining weight within 12 days of being injected with SR9009 and all without their insulin tolerance or glucose levels being affected.

Sr9009 weight loss

  1. Can Lower Blood Cholesterol

Mice that were given SR9009 for 7 to 10 days had significantly reduced cholesterol and triglyceride levels.

Another study fed a high cholesterol diet to genetically modified mice to mimic a human-like fat profile and found that after consuming SR9009 for 8 weeks, these mice saw reduced LDL, triglyceride and cholesterol levels. However, it’s important to note that their HDL cholesterol levels remained the same.

  1. Can Boost Endurance

SR9009 has been shown to increase the overall amount of active mitochondria in mice, thus improving their endurance levels considerably.

  1. Can Decrease Inflammation

Thanks to its ability to reduce TNF-alpha production in rats, SR9009 has also been shown to reduce lung inflammation, as well as the production of inflammation molecules in their nerve cells.

  1. Can Prevent Atherosclerosis

Researchers know that genetically modified mice have the tendency to exhibit hardened arteries. That’s why these mice were given SR9009 for 7 weeks, and the result was significantly reduced blood vessel lesions.

  1. Can Help with Heart Disease

Mice that received SR9009 injections for 28 days had better functioning hearts than their counterparts who didn’t get any injection.

  1. Can Increase Wakefulness

Because SR9009 is able to activate REV-ERB, it has the ability to affect sleeping and waking patterns as shown in mice, even though for only a short period of time (12 hours).

Conversely, injecting SR9009 into the mice while it was daylight led to reduced REM or deep sleep, as well as increased energy levels when they were supposed to be asleep. Mice that had SR9009 injected into them at night (when they were supposed to be awake), showed no signs of being affected whatsoever.

This has led researchers to conclude that SR9009 may help humans stay awake at night for studying, working night shifts or traveling.

  1. Can Help with Anxiety

Injecting SR9009 into mice twice per day for up to 10 days showed such reduced anxiety levels that its effects were similar to those of benzodiazepine.

  1. Can Prevent Fibrosis

Mice with scarred livers experienced fast tissue recovery after taking SR9009 for 2 weeks.

SR-9009 Side Effects

There are currently no known side effects of SR9009. Mice research results don’t indicate any signs of liver toxicity, but some have reported cases of insomnia.

SR9009 dosage and how to use it right

Those already using a steroid cycle can just add SR9009 to their existing stack or use it on its own as they prefer. Current data shows that it mixes seamlessly with other steroids without leading to any side-effects.

It has no hormonal properties, which means it won’t cause anything to shut down or lead to undesirable side effects like excess estrogen.

It’s often recommended to cycle SR9009 for 8 weeks off and 8 weeks on so that the body doesn’t get too used to it.

Users are also advised to take SR9009 along with a liver supplement just to be on the safe side, although it hasn’t been shown to have any adverse effects on the liver.

It’s also advised that you take SR9009 only in dosages of 20 to 30 mg per day while making sure to listen to your body throughout.

Just keep in mind that SR9009 has a very short half-life of 4 hours, which means that you’ll have to space out that daily dosage to maintain stability.

This would mean taking 5 mg every 4 hours in order to get the most out of it if you’re getting 20 mg a day.

SR9009 vs. Cardarine (GW501516)

A lot of people rightfully compare Stenabolic to Cardarine (GW501516) because they’re so similar. However, Cardine has a very long half-life of 24 hours, which is a world apart from Stenabolic’s 4 hours.

As a result, most individuals prefer to use Stenabolic as a pre-workout in order to boost endurance levels while promoting fat loss, while Cardarine is used to prolong that endurance and fat burning activity for the whole day. If you would use Stenabolic for muscle gaining purposes you should have a look at LGD-4033, its a real potent SARM for gaining lean muscle mass.

Where to Buy Authentic SR9009?

When shopping for SR9009 it’s important to realize that there are thousands of merchants out there that are selling counterfeit products, with some even containing banned steroids and/or hormones.

That’s why you need to purchase only from reputable vendors like SARMS4YOU, which is known for being a reliable supplier of Stenabolic and other SARMs.

Buy SR-9009

 

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